Grim Favors are mini-objectives that you complete in different regions. Once you collect 10, you can return to the Tree of Whispers for a Diablo IV gold cache that often includes Horadric Vials. This method is highly recommended for players at all levels, especially when other major events are not active.

4. Helpout Quests (Early Game)
Helpout quests are designed to be accessible to all players, including those at lower levels. These simple tasks often reward Horadric Vials and can be completed quickly, making them a great option for new characters or casual farming sessions.

5. Nightmare Dungeons and Horadric Vaults
As you progress into higher-level content, Nightmare Dungeons and Horadric Vaults become the go-to sources for vial farming. These dungeons feature:

High-density elite packs and minibosses.

Multiple loot-heavy chests.

Higher drop rates for rare and valuable items.

Horadric Vaults in particular are well-known for yielding large quantities of Horadric Vials, especially when cleared efficiently on higher world tiers.

6. Horadric Fortress (Endgame)
Once you begin receiving high-tier loot and enter the endgame, the Horadric Fortress becomes a reliable source of vials and other spell-related components. The enemies and rewards here scale with your level and build strength, making it one of cheap D4 Gold the most consistent late-game farming zones.