In addition to farming vials, you will also gain Horadric Knowledge passively by participating in Helltides, completing Nightmare Dungeons, and running the Horadric Vault. As your Horadric Knowledge increases, you unlock Horadric Focus rewards, which are stashes that can hold a Diablo IV gold large number of Horadric Vials. Maximizing your Horadric Knowledge will ensure you gather vials more efficiently as you progress through the game.

Using Horadric Vials Wisely
Horadric Vials are the only resource that can upgrade Horadric spells, and it's crucial to use them wisely to maximize their benefit. Upgrading spells is essential to improving your character's power, but using vials prematurely may lead to wasting them on spells you don't end up using.

Tips for Using Horadric Vials:
Wait to Use Vials: It's recommended to wait before using your Horadric Vials, especially early in the game. You'll unlock several upgradeable spell components as buy Diablo 4 Items you progress, so taking the time to experiment with different spells and builds will help you avoid wasting vials on abilities you might not use in the long term.